Interrogation of novel CDK2/9 inhibitor fadraciclib (CYC065) as a potential therapeutic approach for AML

During the last 50 years, there was a gentle enchancment within the therapy final result of acute myeloid leukemia (AML). Nonetheless, median survival within the aged continues to be poor because of intolerance to intensive chemotherapy and better numbers of sufferers with hostile cytogenetics. Fadraciclib (CYC065), a novel cyclin-dependent kinase (CDK) 2/9 inhibitor, has preclinical efficacy in AML.
In AML cell strains, myeloid cell leukemia 1 (MCL-1) was downregulated following therapy with fadraciclib, leading to a fast induction of apoptosis. As well as, RNA polymerase II (RNAPII)-driven transcription was suppressed, rendering a world gene suppression. Fast induction of apoptosis was noticed in major AML cells after therapy with fadraciclib for 6-Eight h. Twenty-four hours steady therapy additional elevated efficacy of fadraciclib.
Though preliminary outcomes confirmed that AML cell strains harboring KMT2A rearrangement (KMT2A-r) are extra delicate to fadraciclib, we discovered that the drug can induce apoptosis and reduce MCL-1 expression in major AML cells, no matter KMT2A standing. Importantly, the range of genetic mutations noticed in major AML affected person samples was related to variable response to fadraciclib, confirming the necessity for affected person stratification to allow a simpler and customized therapy strategy.
Synergistic exercise was demonstrated when fadraciclib was mixed with the BCL-2 inhibitor venetoclax, or the traditional chemotherapy brokers, cytarabine, or azacitidine, with the mix of fadraciclib and azacitidine having essentially the most favorable therapeutic window. In abstract, these outcomes spotlight the potential of fadraciclib as a novel therapeutic strategy for AML.

Inhibition of Nrf2-mediated glucose metabolism by brusatol synergistically sensitizes acute myeloid leukemia to Ara-C

Chemotherapy resistance stays to be the first barrier to acute myeloid leukemia (AML) therapy failure. Nuclear factor-erythroid 2-related issue 2 (Nrf2) has been effectively established as a really pleiotropic transcription issue. Inhibition of Nrf2 perform will increase the sensitivity of varied chemotherapeutics and overcomes chemoresistance successfully.
Brusatol (Bru) has been reported to lower Nrf2 protein expression particularly by ubiquitin degradation of Nrf2. Nonetheless, it stays elusive whether or not mixture of Brusatol and Cytarabine (Ara-C) elicits a synergistic antitumor impact in AML. Our outcomes demonstrated that mixture of Ara-C and Brusatol synergistically exerted exceptional pro-apoptosis impact in HL-60 and THP-1 cells. Mechanistically, synergistic anti-tumor impact of Ara-C/Brusatol in AML cells is mediated by attenuating Nrf2 expression.
To our shock, Nrf2 inhibition by Brusatol causes downregulation of the expression of glycolysis-related proteins and decreased glucose consumption and lactate manufacturing, whereas the extent of ROS manufacturing was unaffected. The activation of Nrf2 by Sulforaphane (SFP) may reverse the chemotherapeutic impact and adjustments of glycolysis of concomitant of Ara-C with Brusatol in AML cell strains.
Moreover, Ara-C/Brusatol co-treatment decreased Glucose-6-phosphate dehydrogenase (G6PD) protein expression and elevated the sensitivity of Ara-C. Furthermore, the mouse xenograft in vivo experiment confirmed that combining Ara-C with Brusatol exerted stronger antileukemia than Ara-C alone. The efficacy, along with the mechanistic observations, reveals the potential of concurrently giving these two medication and offers a rational foundation for focusing on glucose catabolism in future scientific therapeutic strategy.

Utility of a Easy Microfluidic Chip Evaluation Expertise to Consider the Inhibitory Function of Protocatechuic Acid on Shear-Induced Platelet Aggregation

This research aimed to develop a easy microfluidic chip evaluation know-how to review the inhibitory impact of protocatechuic acid on shear-induced platelet aggregation. The microfluidic chip designed on this research simulates 80% fastened slim microchannels. This microchannel slim mannequin makes use of the finite factor evaluation module of the three-dimensional modeling software program solidwork to research fluid dynamic habits. Blood handled with protocatechuic acid at 1, 2, 4, 8, or 16 µg/mL was handed via the microchannel stenosis mannequin at a shear fee of 10,000 s-1. The platelet adhesion and aggregation behaviors have been then measured utilizing fluorescence microscopy and noticed in actual time.
 Interrogation of novel CDK2/9 inhibitor fadraciclib (CYC065) as a potential therapeutic approach for AML
Concurrently, the antiplatelet aggregation impact of protocatechuic acid was analyzed utilizing thromboelastography and photoelectric turbidimetry. The designed stenosis mannequin of the microfluidic chip can produce a gradient of fluid shear fee, and the gradient of fluid shear fee can induce platelet aggregation. Underneath this mannequin, the diploma of platelet adhesion and aggregation elevated because the shear fee elevated.
Within the experimental focus vary of 0-8 µmol/mL, protocatechuic acid exerted a concentration-dependent inhibition of platelet aggregation. In distinction, thromboelastography and photoelectric turbidimetry didn’t exhibit an inhibitory impact. The microfluidic chip evaluation know-how developed on this research can be utilized to review the impact of protocatechin in inhibiting platelet aggregation induced by shear fee in vitro. This know-how is straightforward to function and can be utilized as a brand new sort of antiplatelet aggregation evaluation know-how for screening research of novel potential antiplatelet aggregation medication.

A neuroimaging dataset on response inhibition and selective consideration in adults and kids with and with out ADHD

On this article we describe the dataset titled “Response inhibition and selective consideration in adults and kids with and with out ADHD” which is publicly obtainable on OpenNeuro.org. This dataset is comprised of neuroimaging and standardized cognitive evaluation scores from 11 adults, 12 youngsters recognized with Consideration Deficit Hyperactivity Dysfunction (ADHD) and 15 age matched youngsters with out ADHD.

Mouse Ribonuclease Inhibitor (RI) Protein

20-abx068926
  • EUR 704.00
  • EUR 286.00
  • EUR 2165.00
  • EUR 829.00
  • EUR 495.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Ribonuclease Inhibitor (RI) Polyclonal Antibody (Mouse)

4-PAB444Mu01
  • EUR 243.00
  • EUR 2457.00
  • EUR 613.00
  • EUR 305.00
  • EUR 212.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Ribonuclease Inhibitor (RI)

Ribonuclease Inhibitor (RI) Polyclonal Antibody (Human, Mouse)

4-PAB444Hu01
  • EUR 239.00
  • EUR 2391.00
  • EUR 598.00
  • EUR 299.00
  • EUR 211.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human, Mouse Ribonuclease Inhibitor (RI)

Ribonuclease Inhibitor (RI) Polyclonal Antibody (Mouse), APC

4-PAB444Mu01-APC
  • EUR 340.00
  • EUR 3203.00
  • EUR 894.00
  • EUR 432.00
  • EUR 217.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Ribonuclease Inhibitor (RI). This antibody is labeled with APC.

Ribonuclease Inhibitor (RI) Polyclonal Antibody (Mouse), Biotinylated

4-PAB444Mu01-Biotin
  • EUR 307.00
  • EUR 2407.00
  • EUR 714.00
  • EUR 375.00
  • EUR 217.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Ribonuclease Inhibitor (RI). This antibody is labeled with Biotin.

Ribonuclease Inhibitor (RI) Polyclonal Antibody (Mouse), Cy3

4-PAB444Mu01-Cy3
  • EUR 411.00
  • EUR 4229.00
  • EUR 1151.00
  • EUR 535.00
  • EUR 248.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Ribonuclease Inhibitor (RI). This antibody is labeled with Cy3.

Ribonuclease Inhibitor (RI) Polyclonal Antibody (Mouse), FITC

4-PAB444Mu01-FITC
  • EUR 292.00
  • EUR 2582.00
  • EUR 735.00
  • EUR 366.00
  • EUR 194.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Ribonuclease Inhibitor (RI). This antibody is labeled with FITC.

Ribonuclease Inhibitor (RI) Polyclonal Antibody (Mouse), HRP

4-PAB444Mu01-HRP
  • EUR 311.00
  • EUR 2792.00
  • EUR 791.00
  • EUR 391.00
  • EUR 205.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Ribonuclease Inhibitor (RI). This antibody is labeled with HRP.

Ribonuclease Inhibitor (RI) Polyclonal Antibody (Mouse), PE

4-PAB444Mu01-PE
  • EUR 292.00
  • EUR 2582.00
  • EUR 735.00
  • EUR 366.00
  • EUR 194.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Ribonuclease Inhibitor (RI). This antibody is labeled with PE.

Ribonuclease Inhibitor (RI) Polyclonal Antibody (Human, Rat)

4-PAB444Ra01
  • EUR 251.00
  • EUR 2576.00
  • EUR 640.00
  • EUR 316.00
  • EUR 215.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human, Rat Ribonuclease Inhibitor (RI)

Human Ribonuclease Inhibitor (RI) CLIA Kit

abx197652-96tests 96 tests
EUR 825

Human Ribonuclease Inhibitor(RI)ELISA Kit

QY-E03158 96T
EUR 361

Ribonuclease Inhibitor (RI) Polyclonal Antibody (Human, Mouse), APC

4-PAB444Hu01-APC
  • EUR 333.00
  • EUR 3113.00
  • EUR 872.00
  • EUR 423.00
  • EUR 215.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human, Mouse Ribonuclease Inhibitor (RI). This antibody is labeled with APC.

Ribonuclease Inhibitor (RI) Polyclonal Antibody (Human, Mouse), Biotinylated

4-PAB444Hu01-Biotin
  • EUR 303.00
  • EUR 2341.00
  • EUR 697.00
  • EUR 369.00
  • EUR 216.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human, Mouse Ribonuclease Inhibitor (RI). This antibody is labeled with Biotin.

Ribonuclease Inhibitor (RI) Polyclonal Antibody (Human, Mouse), Cy3

4-PAB444Hu01-Cy3
  • EUR 403.00
  • EUR 4109.00
  • EUR 1121.00
  • EUR 523.00
  • EUR 245.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human, Mouse Ribonuclease Inhibitor (RI). This antibody is labeled with Cy3.

Ribonuclease Inhibitor (RI) Polyclonal Antibody (Human, Mouse), FITC

4-PAB444Hu01-FITC
  • EUR 287.00
  • EUR 2510.00
  • EUR 717.00
  • EUR 359.00
  • EUR 192.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human, Mouse Ribonuclease Inhibitor (RI). This antibody is labeled with FITC.

Ribonuclease Inhibitor (RI) Polyclonal Antibody (Human, Mouse), HRP

4-PAB444Hu01-HRP
  • EUR 305.00
  • EUR 2714.00
  • EUR 772.00
  • EUR 383.00
  • EUR 203.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human, Mouse Ribonuclease Inhibitor (RI). This antibody is labeled with HRP.

Ribonuclease Inhibitor (RI) Polyclonal Antibody (Human, Mouse), PE

4-PAB444Hu01-PE
  • EUR 287.00
  • EUR 2510.00
  • EUR 717.00
  • EUR 359.00
  • EUR 192.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human, Mouse Ribonuclease Inhibitor (RI). This antibody is labeled with PE.

Ribonuclease Inhibitor (RI) Polyclonal Antibody (Mouse), APC-Cy7

4-PAB444Mu01-APC-Cy7
  • EUR 560.00
  • EUR 6286.00
  • EUR 1669.00
  • EUR 745.00
  • EUR 315.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Ribonuclease Inhibitor (RI). This antibody is labeled with APC-Cy7.

Ribonuclease Inhibitor (RI) Polyclonal Antibody (Human, Rat), APC

4-PAB444Ra01-APC
  • EUR 351.00
  • EUR 3365.00
  • EUR 935.00
  • EUR 449.00
  • EUR 222.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human, Rat Ribonuclease Inhibitor (RI). This antibody is labeled with APC.

Ribonuclease Inhibitor (RI) Polyclonal Antibody (Human, Rat), Biotinylated

4-PAB444Ra01-Biotin
  • EUR 316.00
  • EUR 2526.00
  • EUR 744.00
  • EUR 387.00
  • EUR 221.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human, Rat Ribonuclease Inhibitor (RI). This antibody is labeled with Biotin.

Ribonuclease Inhibitor (RI) Polyclonal Antibody (Human, Rat), Cy3

4-PAB444Ra01-Cy3
  • EUR 427.00
  • EUR 4445.00
  • EUR 1205.00
  • EUR 557.00
  • EUR 254.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human, Rat Ribonuclease Inhibitor (RI). This antibody is labeled with Cy3.

Ribonuclease Inhibitor (RI) Polyclonal Antibody (Human, Rat), FITC

4-PAB444Ra01-FITC
  • EUR 301.00
  • EUR 2712.00
  • EUR 768.00
  • EUR 379.00
  • EUR 197.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human, Rat Ribonuclease Inhibitor (RI). This antibody is labeled with FITC.

Ribonuclease Inhibitor (RI) Polyclonal Antibody (Human, Rat), HRP

4-PAB444Ra01-HRP
  • EUR 321.00
  • EUR 2933.00
  • EUR 827.00
  • EUR 405.00
  • EUR 209.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human, Rat Ribonuclease Inhibitor (RI). This antibody is labeled with HRP.

Ribonuclease Inhibitor (RI) Polyclonal Antibody (Human, Rat), PE

4-PAB444Ra01-PE
  • EUR 301.00
  • EUR 2712.00
  • EUR 768.00
  • EUR 379.00
  • EUR 197.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human, Rat Ribonuclease Inhibitor (RI). This antibody is labeled with PE.

CLIA kit for Human RI (Ribonuclease Inhibitor)

E-CL-H0899 1 plate of 96 wells
EUR 584
Description: A sandwich CLIA kit for quantitative measurement of Human RI (Ribonuclease Inhibitor) in samples from Serum, Plasma, Cell supernatant

ELISA kit for Human RI (Ribonuclease Inhibitor)

E-EL-H1382 1 plate of 96 wells
EUR 534
Description: A sandwich ELISA kit for quantitative measurement of Human RI (Ribonuclease Inhibitor) in samples from Serum, Plasma, Cell supernatant

Ribonuclease Inhibitor (RI) Polyclonal Antibody (Human, Mouse), APC-Cy7

4-PAB444Hu01-APC-Cy7
  • EUR 547.00
  • EUR 6106.00
  • EUR 1624.00
  • EUR 727.00
  • EUR 310.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human, Mouse Ribonuclease Inhibitor (RI). This antibody is labeled with APC-Cy7.

Ribonuclease Inhibitor (RI) Polyclonal Antibody (Human, Rat), APC-Cy7

4-PAB444Ra01-APC-Cy7
  • EUR 583.00
  • EUR 6610.00
  • EUR 1750.00
  • EUR 778.00
  • EUR 324.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human, Rat Ribonuclease Inhibitor (RI). This antibody is labeled with APC-Cy7.

anti-Ribonuclease Inhibitor

YF-PA14406 50 ug
EUR 363
Description: Mouse polyclonal to Ribonuclease Inhibitor

anti-Ribonuclease Inhibitor

YF-PA14407 100 ul
EUR 403
Description: Rabbit polyclonal to Ribonuclease Inhibitor

anti-Ribonuclease Inhibitor

YF-PA14408 100 ug
EUR 403
Description: Rabbit polyclonal to Ribonuclease Inhibitor

anti-Ribonuclease Inhibitor

YF-PA24588 50 ul
EUR 334
Description: Mouse polyclonal to Ribonuclease Inhibitor

Anti-Ribonuclease Inhibitor/RNH1 Antibody

PB9885 100ug/vial
EUR 334

Anti-Ribonuclease Inhibitor (3F5)

YF-MA15221 100 ug
EUR 363
Description: Mouse monoclonal to Ribonuclease Inhibitor

Ribonuclease inhibitor Antibody

20-abx137320
  • EUR 704.00
  • EUR 328.00
  • EUR 230.00
  • 100 ug
  • 20 ug
  • 5 ug

Ribonuclease inhibitor

RB0478 5KU
EUR 154.4

Rabbit Polyclonal antibody Anti-CRBN

Anti-CRBN 50 µg
EUR 349

Anti-CRF-RI antibody

STJ96855 200 µl
EUR 197
Description: Rabbit polyclonal to CRF-RI.

Anti-CRF-RI antibody

STJ92473 200 µl
EUR 197
Description: Rabbit polyclonal to CRF-RI.

Placenta Ribonuclease Inhibitor

Z5040001 5000 units
EUR 316
Description: Working with the fragile RNA molecules requires a great deal of caution, especially when it comes to protecting them from all the RNases that are virtually everywhere. Ensure a successful reverse transcription PCR by protecting you RNAs with our RNase inhibitor.

RNaseOFF ribonuclease Inhibitor

M1238-4000
EUR 256

Anti-mouse TNF-RI antibody

STJ16100930 1 mL
EUR 451

Anti-TG beta RI antibody

STJ95992 200 µl
EUR 197
Description: Rabbit polyclonal to TGFbeta RI.

anti-Fc epsilon RI

YF-PA11731 100 ug
EUR 403
Description: Rabbit polyclonal to Fc epsilon RI

anti-Fc epsilon RI

YF-PA23697 50 ul
EUR 334
Description: Mouse polyclonal to Fc epsilon RI

Ribonuclease/Angiogenin Inhibitor 1 (RNH1) Antibody

20-abx115215
  • EUR 732.00
  • EUR 398.00
  • 150 ul
  • 50 ul

Ribonuclease/angiogenin Inhibitor 1 (RNH1) Antibody

20-abx003000
  • EUR 411.00
  • EUR 592.00
  • EUR 182.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Ribonuclease/angiogenin Inhibitor 1 (RNH1) Antibody

abx026812-400ul 400 ul
EUR 523

Ribonuclease/angiogenin Inhibitor 1 (RNH1) Antibody

abx026812-80l 80 µl
EUR 286

Ribonuclease/angiogenin Inhibitor 1 (RNH1) Antibody

abx237365-100ug 100 ug
EUR 509

Ribonuclease/angiogenin Inhibitor 1 (RNH1) Antibody

abx237366-100ug 100 ug
EUR 551

Ribonuclease/angiogenin Inhibitor 1 (RNH1) Antibody

20-abx211145
  • EUR 411.00
  • EUR 300.00
  • 100 ul
  • 50 ul

Ribonuclease/angiogenin Inhibitor 1 (RNH1) Antibody

20-abx211146
  • EUR 411.00
  • EUR 300.00
  • 100 ul
  • 50 ul

anti- Fc epsilon RI alpha antibody

FNab03058 100µg
EUR 585
Description: Antibody raised against Fc epsilon RI alpha

Anti-Fc epsilon RI alpha antibody

PAab03058 100 ug
EUR 412

Anti-Ribonuclease 7 Antibody

STJ60034 100 µg
EUR 424

Anti-Ribonuclease 7 Antibody

STJ60035 100 µg
EUR 424

Anti-Ribonuclease 7 Antibody

STJ60036 100 µg
EUR 424

Anti-ribonuclease 8 Antibody

STJ60037 100 µg
EUR 424

Rat Ribonuclease Inhibitor ELISA kit

E02R0052-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Rat Ribonuclease Inhibitor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Ribonuclease Inhibitor ELISA kit

E02R0052-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Rat Ribonuclease Inhibitor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Ribonuclease Inhibitor ELISA kit

E02R0052-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Rat Ribonuclease Inhibitor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Ribonuclease Inhibitor ELISA kit

E09R0052-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Monkey Ribonuclease Inhibitor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Ribonuclease Inhibitor ELISA kit

E09R0052-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Monkey Ribonuclease Inhibitor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Ribonuclease Inhibitor ELISA kit

E09R0052-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Monkey Ribonuclease Inhibitor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Ribonuclease Inhibitor ELISA kit

E08R0052-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Canine Ribonuclease Inhibitor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Ribonuclease Inhibitor ELISA kit

E08R0052-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Canine Ribonuclease Inhibitor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Ribonuclease Inhibitor ELISA kit

E08R0052-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Canine Ribonuclease Inhibitor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Ribonuclease Inhibitor ELISA kit

E01R0052-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Human Ribonuclease Inhibitor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Ribonuclease Inhibitor ELISA kit

E01R0052-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Human Ribonuclease Inhibitor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Ribonuclease Inhibitor ELISA kit

E01R0052-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Human Ribonuclease Inhibitor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Ribonuclease Inhibitor ELISA kit

E07R0052-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Porcine Ribonuclease Inhibitor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Ribonuclease Inhibitor ELISA kit

E07R0052-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Porcine Ribonuclease Inhibitor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Ribonuclease Inhibitor ELISA kit

E07R0052-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Porcine Ribonuclease Inhibitor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Ribonuclease Inhibitor ELISA kit

E04R0052-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Rabbit Ribonuclease Inhibitor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Ribonuclease Inhibitor ELISA kit

E04R0052-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Rabbit Ribonuclease Inhibitor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Ribonuclease Inhibitor ELISA kit

E04R0052-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Rabbit Ribonuclease Inhibitor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Ribonuclease Inhibitor ELISA kit

E06R0052-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Goat Ribonuclease Inhibitor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Ribonuclease Inhibitor ELISA kit

E06R0052-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Goat Ribonuclease Inhibitor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Ribonuclease Inhibitor ELISA kit

E06R0052-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Goat Ribonuclease Inhibitor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Ribonuclease Inhibitor ELISA kit

E03R0052-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Mouse Ribonuclease Inhibitor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Ribonuclease Inhibitor ELISA kit

E03R0052-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Mouse Ribonuclease Inhibitor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Ribonuclease Inhibitor ELISA kit

E03R0052-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Mouse Ribonuclease Inhibitor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Anti-Phospho-TG beta RI (S165) antibody

STJ91351 200 µl
EUR 197
Description: TGFbeta RI is a protein encoded by the TGFBR1 gene which is approximately 55,9 kDa. TGFbeta RI is localised to the cell membrane. It is involved in apoptotic pathways and the PAK pathway. It is a heteromeric complex that transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation, differentiation and extracellular matrix production. TGFbeta RI is expressed in all human tissues and is most abundant in the placenta. Mutations in the TGFBR1 gene may result in Loeys-Dietz syndrome. STJ91351 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This primary antibody specifically binds to endogenous TGFbeta R protein which only binds about S165 when S165 is phosphorylated.

anti-Ribonuclease T2

YF-PA15757 50 ug
EUR 363
Description: Mouse polyclonal to Ribonuclease T2

Anti-Ribonuclease A/RNASE1 Antibody

PA1507 100ug/vial
EUR 294

Anti-Ribonuclease 3/RNASE3 Antibody

A03115-1 100ug/vial
EUR 334

Human RNH1/ Ribonuclease inhibitor ELISA Kit

E2837Hu 1 Kit
EUR 571

Mouse Rnh1/ Ribonuclease inhibitor ELISA Kit

E1275Mo 1 Kit
EUR 571

Mouse Ribonuclease inhibitor (RNH1) ELISA Kit

abx516953-96tests 96 tests
EUR 668

Pig Ribonuclease Inhibitor (RNH1) ELISA Kit

abx516954-96tests 96 tests
EUR 825

Rat Ribonuclease inhibitor (RNH1) ELISA Kit

abx516955-96tests 96 tests
EUR 668

Rabbit Ribonuclease Inhibitor (RNH1) ELISA Kit

abx363762-96tests 96 tests
EUR 825

Pig Ribonuclease Inhibitor (RNH1) ELISA Kit

abx361392-96tests 96 tests
EUR 825

Chicken Ribonuclease Inhibitor (RNH1) ELISA Kit

abx356259-96tests 96 tests
EUR 825

Monkey Ribonuclease Inhibitor (RNH1) ELISA Kit

abx359624-96tests 96 tests
EUR 825

Human Ribonuclease inhibitor (RNH1) ELISA Kit

abx253105-96tests 96 tests
EUR 707

Human Ribonuclease inhibitor (RNH1) ELISA Kit

abx250903-96tests 96 tests
EUR 707

ELISA kit for Human Ribonuclease inhibitor

EK3409 96 tests
EUR 553
Description: Enzyme-linked immunosorbent assay kit for quantification of Human Ribonuclease inhibitor in samples from serum, plasma, tissue homogenates and other biological fluids.

Human RNH1(Ribonuclease inhibitor) ELISA Kit

EH1611 96T
EUR 567.6
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.938 ng/ml

Human Ribonuclease inhibitor, RNH1 ELISA KIT

ELI-04719h 96 Tests
EUR 824

Mouse Ribonuclease inhibitor, Rnh1 ELISA KIT

ELI-04721m 96 Tests
EUR 865

Porcine Ribonuclease inhibitor, RNH1 ELISA KIT

ELI-04722p 96 Tests
EUR 928

Guinea pig Ribonuclease Inhibitor ELISA kit

E05R0052-192T 192 tests
EUR 1270
Description: A competitive ELISA for quantitative measurement of Guinea pig Ribonuclease Inhibitor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig Ribonuclease Inhibitor ELISA kit

E05R0052-48 1 plate of 48 wells
EUR 520
Description: A competitive ELISA for quantitative measurement of Guinea pig Ribonuclease Inhibitor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig Ribonuclease Inhibitor ELISA kit

E05R0052-96 1 plate of 96 wells
EUR 685
Description: A competitive ELISA for quantitative measurement of Guinea pig Ribonuclease Inhibitor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

RI-1

HY-15317 5mg
EUR 153

RI-2

HY-16904 100mg
EUR 2943

RI-2

B5881-10 10 mg
EUR 514
Description: Description:IC50: 44.17 ?MHomologous recombination (HR) is an essential process in cells that provides repair of DNA double-strand breaks and lesions that block DNA replication. RAD51 is an evolutionarily conserved protein that is central to HR.

RI-2

B5881-5.1 10 mM (in 1mL DMSO)
EUR 374
Description: Description:IC50: 44.17 ?MHomologous recombination (HR) is an essential process in cells that provides repair of DNA double-strand breaks and lesions that block DNA replication. RAD51 is an evolutionarily conserved protein that is central to HR.

RI-2

B5881-50 50 mg
EUR 1442
Description: Description:IC50: 44.17 ?MHomologous recombination (HR) is an essential process in cells that provides repair of DNA double-strand breaks and lesions that block DNA replication. RAD51 is an evolutionarily conserved protein that is central to HR.

RI-1

A3764-10 10 mg
EUR 200
Description: RI-1 Description:IC50: 5~30 ?M [1]RAD51 is a eukaryote gene, encoding RAD51 protein that participates in DNA damage induction and complex signal pathway of cell cycle checkpoint of homologous recombination in cells.

RI-1

A3764-5 5 mg
EUR 137
Description: RI-1 Description:IC50: 5~30 ?M [1]RAD51 is a eukaryote gene, encoding RAD51 protein that participates in DNA damage induction and complex signal pathway of cell cycle checkpoint of homologous recombination in cells.

RI-1

A3764-5.1 10 mM (in 1mL DMSO)
EUR 145
Description: RI-1 Description:IC50: 5~30 ?M [1]RAD51 is a eukaryote gene, encoding RAD51 protein that participates in DNA damage induction and complex signal pathway of cell cycle checkpoint of homologous recombination in cells.

RI-1

A3764-50 50 mg
EUR 630
Description: RI-1 Description:IC50: 5~30 ?M [1]RAD51 is a eukaryote gene, encoding RAD51 protein that participates in DNA damage induction and complex signal pathway of cell cycle checkpoint of homologous recombination in cells.

Suavissimoside RI

TBW01280 10mg Ask for price

RI-1

B1823-25
EUR 544

RI-1

B1823-5
EUR 175

Anti-Fc epsilon RI (2C12-3B6)

YF-MA10319 100 ug
EUR 363
Description: Mouse monoclonal to Fc epsilon RI

CRF-RI Polyclonal Antibody

ES4220-100ul 100ul
EUR 279
Description: A Rabbit Polyclonal antibody against CRF-RI from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA

CRF-RI Polyclonal Antibody

ES4220-50ul 50ul
EUR 207
Description: A Rabbit Polyclonal antibody against CRF-RI from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA

TGF? RI Polyclonal Antibody

ES3594-50ul 50ul
EUR 207
Description: A Rabbit Polyclonal antibody against TGF? RI from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IF, WB, ELISA

TGF? RI Polyclonal Antibody

ES3594-100ul 100ul
EUR 279
Description: A Rabbit Polyclonal antibody against TGF? RI from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IF, WB, ELISA

CRF-RI Polyclonal Antibody

ES2050-100ul 100ul
EUR 279
Description: A Rabbit Polyclonal antibody against CRF-RI from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA

CRF-RI Polyclonal Antibody

ES2050-50ul 50ul
EUR 207
Description: A Rabbit Polyclonal antibody against CRF-RI from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA
Useful Magnetic Resonance Imaging (fMRI) information have been collected whereas contributors accomplished selective consideration and response inhibition duties designed and balanced for inside or cross-task comparisons. Earlier analysis using this dataset has but to discover associations between mind perform and cognitive evaluation scores or variations in neural processes throughout stimuli options making this dataset helpful for its future contributions to the sector in addition to replication of prior findings.

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