Interrogation of novel CDK2/9 inhibitor fadraciclib (CYC065) as a potential therapeutic approach for AML

During the last 50 years, there was a gentle enchancment within the therapy final result of acute myeloid leukemia (AML). Nonetheless, median survival within the aged continues to be poor because of intolerance to intensive chemotherapy and better numbers of sufferers with hostile cytogenetics. Fadraciclib (CYC065), a novel cyclin-dependent kinase (CDK) 2/9 inhibitor, has preclinical efficacy in AML.
In AML cell strains, myeloid cell leukemia 1 (MCL-1) was downregulated following therapy with fadraciclib, leading to a fast induction of apoptosis. As well as, RNA polymerase II (RNAPII)-driven transcription was suppressed, rendering a world gene suppression. Fast induction of apoptosis was noticed in major AML cells after therapy with fadraciclib for 6-Eight h. Twenty-four hours steady therapy additional elevated efficacy of fadraciclib.
Though preliminary outcomes confirmed that AML cell strains harboring KMT2A rearrangement (KMT2A-r) are extra delicate to fadraciclib, we discovered that the drug can induce apoptosis and reduce MCL-1 expression in major AML cells, no matter KMT2A standing. Importantly, the range of genetic mutations noticed in major AML affected person samples was related to variable response to fadraciclib, confirming the necessity for affected person stratification to allow a simpler and customized therapy strategy.
Synergistic exercise was demonstrated when fadraciclib was mixed with the BCL-2 inhibitor venetoclax, or the traditional chemotherapy brokers, cytarabine, or azacitidine, with the mix of fadraciclib and azacitidine having essentially the most favorable therapeutic window. In abstract, these outcomes spotlight the potential of fadraciclib as a novel therapeutic strategy for AML.

Inhibition of Nrf2-mediated glucose metabolism by brusatol synergistically sensitizes acute myeloid leukemia to Ara-C

Chemotherapy resistance stays to be the first barrier to acute myeloid leukemia (AML) therapy failure. Nuclear factor-erythroid 2-related issue 2 (Nrf2) has been effectively established as a really pleiotropic transcription issue. Inhibition of Nrf2 perform will increase the sensitivity of varied chemotherapeutics and overcomes chemoresistance successfully.
Brusatol (Bru) has been reported to lower Nrf2 protein expression particularly by ubiquitin degradation of Nrf2. Nonetheless, it stays elusive whether or not mixture of Brusatol and Cytarabine (Ara-C) elicits a synergistic antitumor impact in AML. Our outcomes demonstrated that mixture of Ara-C and Brusatol synergistically exerted exceptional pro-apoptosis impact in HL-60 and THP-1 cells. Mechanistically, synergistic anti-tumor impact of Ara-C/Brusatol in AML cells is mediated by attenuating Nrf2 expression.
To our shock, Nrf2 inhibition by Brusatol causes downregulation of the expression of glycolysis-related proteins and decreased glucose consumption and lactate manufacturing, whereas the extent of ROS manufacturing was unaffected. The activation of Nrf2 by Sulforaphane (SFP) may reverse the chemotherapeutic impact and adjustments of glycolysis of concomitant of Ara-C with Brusatol in AML cell strains.
Moreover, Ara-C/Brusatol co-treatment decreased Glucose-6-phosphate dehydrogenase (G6PD) protein expression and elevated the sensitivity of Ara-C. Furthermore, the mouse xenograft in vivo experiment confirmed that combining Ara-C with Brusatol exerted stronger antileukemia than Ara-C alone. The efficacy, along with the mechanistic observations, reveals the potential of concurrently giving these two medication and offers a rational foundation for focusing on glucose catabolism in future scientific therapeutic strategy.

Utility of a Easy Microfluidic Chip Evaluation Expertise to Consider the Inhibitory Function of Protocatechuic Acid on Shear-Induced Platelet Aggregation

This research aimed to develop a easy microfluidic chip evaluation know-how to review the inhibitory impact of protocatechuic acid on shear-induced platelet aggregation. The microfluidic chip designed on this research simulates 80% fastened slim microchannels. This microchannel slim mannequin makes use of the finite factor evaluation module of the three-dimensional modeling software program solidwork to research fluid dynamic habits. Blood handled with protocatechuic acid at 1, 2, 4, 8, or 16 µg/mL was handed via the microchannel stenosis mannequin at a shear fee of 10,000 s-1. The platelet adhesion and aggregation behaviors have been then measured utilizing fluorescence microscopy and noticed in actual time.
 Interrogation of novel CDK2/9 inhibitor fadraciclib (CYC065) as a potential therapeutic approach for AML
Concurrently, the antiplatelet aggregation impact of protocatechuic acid was analyzed utilizing thromboelastography and photoelectric turbidimetry. The designed stenosis mannequin of the microfluidic chip can produce a gradient of fluid shear fee, and the gradient of fluid shear fee can induce platelet aggregation. Underneath this mannequin, the diploma of platelet adhesion and aggregation elevated because the shear fee elevated.
Within the experimental focus vary of 0-8 µmol/mL, protocatechuic acid exerted a concentration-dependent inhibition of platelet aggregation. In distinction, thromboelastography and photoelectric turbidimetry didn’t exhibit an inhibitory impact. The microfluidic chip evaluation know-how developed on this research can be utilized to review the impact of protocatechin in inhibiting platelet aggregation induced by shear fee in vitro. This know-how is straightforward to function and can be utilized as a brand new sort of antiplatelet aggregation evaluation know-how for screening research of novel potential antiplatelet aggregation medication.

A neuroimaging dataset on response inhibition and selective consideration in adults and kids with and with out ADHD

On this article we describe the dataset titled “Response inhibition and selective consideration in adults and kids with and with out ADHD” which is publicly obtainable on OpenNeuro.org. This dataset is comprised of neuroimaging and standardized cognitive evaluation scores from 11 adults, 12 youngsters recognized with Consideration Deficit Hyperactivity Dysfunction (ADHD) and 15 age matched youngsters with out ADHD.

Mouse Ribonuclease Inhibitor (RI) Protein

20-abx068926
  • EUR 844.80
  • EUR 343.20
  • EUR 2598.00
  • EUR 994.80
  • EUR 594.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Ribonuclease Inhibitor (RI) Polyclonal Antibody (Mouse)

4-PAB444Mu01
  • EUR 291.60
  • EUR 2948.40
  • EUR 735.60
  • EUR 366.00
  • EUR 254.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Ribonuclease Inhibitor (RI)

Human Ribonuclease Inhibitor (RI) CLIA Kit

abx197652-96tests 96 tests
EUR 990

Human Ribonuclease Inhibitor(RI)ELISA Kit

QY-E03158 96T
EUR 433.2

Ribonuclease Inhibitor (RI) Polyclonal Antibody (Human, Mouse)

4-PAB444Hu01
  • EUR 286.80
  • EUR 2869.20
  • EUR 717.60
  • EUR 358.80
  • EUR 253.20
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human, Mouse Ribonuclease Inhibitor (RI)

Ribonuclease Inhibitor (RI) Polyclonal Antibody (Mouse), APC

4-PAB444Mu01-APC
  • EUR 408.00
  • EUR 3843.60
  • EUR 1072.80
  • EUR 518.40
  • EUR 260.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Ribonuclease Inhibitor (RI). This antibody is labeled with APC.

Ribonuclease Inhibitor (RI) Polyclonal Antibody (Mouse), Biotinylated

4-PAB444Mu01-Biotin
  • EUR 368.40
  • EUR 2888.40
  • EUR 856.80
  • EUR 450.00
  • EUR 260.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Ribonuclease Inhibitor (RI). This antibody is labeled with Biotin.

Ribonuclease Inhibitor (RI) Polyclonal Antibody (Mouse), Cy3

4-PAB444Mu01-Cy3
  • EUR 493.20
  • EUR 5074.80
  • EUR 1381.20
  • EUR 642.00
  • EUR 297.60
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Ribonuclease Inhibitor (RI). This antibody is labeled with Cy3.

Ribonuclease Inhibitor (RI) Polyclonal Antibody (Mouse), FITC

4-PAB444Mu01-FITC
  • EUR 350.40
  • EUR 3098.40
  • EUR 882.00
  • EUR 439.20
  • EUR 232.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Ribonuclease Inhibitor (RI). This antibody is labeled with FITC.

Ribonuclease Inhibitor (RI) Polyclonal Antibody (Mouse), HRP

4-PAB444Mu01-HRP
  • EUR 373.20
  • EUR 3350.40
  • EUR 949.20
  • EUR 469.20
  • EUR 246.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Ribonuclease Inhibitor (RI). This antibody is labeled with HRP.

Ribonuclease Inhibitor (RI) Polyclonal Antibody (Mouse), PE

4-PAB444Mu01-PE
  • EUR 350.40
  • EUR 3098.40
  • EUR 882.00
  • EUR 439.20
  • EUR 232.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Ribonuclease Inhibitor (RI). This antibody is labeled with PE.

Ribonuclease Inhibitor (RI) Polyclonal Antibody (Human, Rat)

4-PAB444Ra01
  • EUR 301.20
  • EUR 3091.20
  • EUR 768.00
  • EUR 379.20
  • EUR 258.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human, Rat Ribonuclease Inhibitor (RI)

Ribonuclease Inhibitor (RI) Polyclonal Antibody (Human, Mouse), APC

4-PAB444Hu01-APC
  • EUR 399.60
  • EUR 3735.60
  • EUR 1046.40
  • EUR 507.60
  • EUR 258.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human, Mouse Ribonuclease Inhibitor (RI). This antibody is labeled with APC.

Ribonuclease Inhibitor (RI) Polyclonal Antibody (Human, Mouse), Biotinylated

4-PAB444Hu01-Biotin
  • EUR 363.60
  • EUR 2809.20
  • EUR 836.40
  • EUR 442.80
  • EUR 259.20
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human, Mouse Ribonuclease Inhibitor (RI). This antibody is labeled with Biotin.

Ribonuclease Inhibitor (RI) Polyclonal Antibody (Human, Mouse), Cy3

4-PAB444Hu01-Cy3
  • EUR 483.60
  • EUR 4930.80
  • EUR 1345.20
  • EUR 627.60
  • EUR 294.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human, Mouse Ribonuclease Inhibitor (RI). This antibody is labeled with Cy3.

Ribonuclease Inhibitor (RI) Polyclonal Antibody (Human, Mouse), FITC

4-PAB444Hu01-FITC
  • EUR 344.40
  • EUR 3012.00
  • EUR 860.40
  • EUR 430.80
  • EUR 230.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human, Mouse Ribonuclease Inhibitor (RI). This antibody is labeled with FITC.

Ribonuclease Inhibitor (RI) Polyclonal Antibody (Human, Mouse), HRP

4-PAB444Hu01-HRP
  • EUR 366.00
  • EUR 3256.80
  • EUR 926.40
  • EUR 459.60
  • EUR 243.60
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human, Mouse Ribonuclease Inhibitor (RI). This antibody is labeled with HRP.

Ribonuclease Inhibitor (RI) Polyclonal Antibody (Human, Mouse), PE

4-PAB444Hu01-PE
  • EUR 344.40
  • EUR 3012.00
  • EUR 860.40
  • EUR 430.80
  • EUR 230.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human, Mouse Ribonuclease Inhibitor (RI). This antibody is labeled with PE.

Ribonuclease Inhibitor (RI) Polyclonal Antibody (Mouse), APC-Cy7

4-PAB444Mu01-APC-Cy7
  • EUR 672.00
  • EUR 7543.20
  • EUR 2002.80
  • EUR 894.00
  • EUR 378.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse Ribonuclease Inhibitor (RI). This antibody is labeled with APC-Cy7.

Ribonuclease Inhibitor (RI) Polyclonal Antibody (Human, Rat), APC

4-PAB444Ra01-APC
  • EUR 421.20
  • EUR 4038.00
  • EUR 1122.00
  • EUR 538.80
  • EUR 266.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human, Rat Ribonuclease Inhibitor (RI). This antibody is labeled with APC.

Ribonuclease Inhibitor (RI) Polyclonal Antibody (Human, Rat), Biotinylated

4-PAB444Ra01-Biotin
  • EUR 379.20
  • EUR 3031.20
  • EUR 892.80
  • EUR 464.40
  • EUR 265.20
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human, Rat Ribonuclease Inhibitor (RI). This antibody is labeled with Biotin.

Ribonuclease Inhibitor (RI) Polyclonal Antibody (Human, Rat), Cy3

4-PAB444Ra01-Cy3
  • EUR 512.40
  • EUR 5334.00
  • EUR 1446.00
  • EUR 668.40
  • EUR 304.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human, Rat Ribonuclease Inhibitor (RI). This antibody is labeled with Cy3.

Ribonuclease Inhibitor (RI) Polyclonal Antibody (Human, Rat), FITC

4-PAB444Ra01-FITC
  • EUR 361.20
  • EUR 3254.40
  • EUR 921.60
  • EUR 454.80
  • EUR 236.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human, Rat Ribonuclease Inhibitor (RI). This antibody is labeled with FITC.

Ribonuclease Inhibitor (RI) Polyclonal Antibody (Human, Rat), HRP

4-PAB444Ra01-HRP
  • EUR 385.20
  • EUR 3519.60
  • EUR 992.40
  • EUR 486.00
  • EUR 250.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human, Rat Ribonuclease Inhibitor (RI). This antibody is labeled with HRP.

Ribonuclease Inhibitor (RI) Polyclonal Antibody (Human, Rat), PE

4-PAB444Ra01-PE
  • EUR 361.20
  • EUR 3254.40
  • EUR 921.60
  • EUR 454.80
  • EUR 236.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human, Rat Ribonuclease Inhibitor (RI). This antibody is labeled with PE.

ELISA kit for Human RI (Ribonuclease Inhibitor)

E-EL-H1382 1 plate of 96 wells
EUR 640.8
Description: A sandwich ELISA kit for quantitative measurement of Human RI (Ribonuclease Inhibitor) in samples from Serum, Plasma, Cell supernatant

CLIA kit for Human RI (Ribonuclease Inhibitor)

E-CL-H0899 1 plate of 96 wells
EUR 700.8
Description: A sandwich CLIA kit for quantitative measurement of Human RI (Ribonuclease Inhibitor) in samples from Serum, Plasma, Cell supernatant

Ribonuclease Inhibitor (RI) Polyclonal Antibody (Human, Mouse), APC-Cy7

4-PAB444Hu01-APC-Cy7
  • EUR 656.40
  • EUR 7327.20
  • EUR 1948.80
  • EUR 872.40
  • EUR 372.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human, Mouse Ribonuclease Inhibitor (RI). This antibody is labeled with APC-Cy7.

Ribonuclease Inhibitor (RI) Polyclonal Antibody (Human, Rat), APC-Cy7

4-PAB444Ra01-APC-Cy7
  • EUR 699.60
  • EUR 7932.00
  • EUR 2100.00
  • EUR 933.60
  • EUR 388.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human, Rat Ribonuclease Inhibitor (RI). This antibody is labeled with APC-Cy7.

anti-Ribonuclease Inhibitor

YF-PA24588 50 ul
EUR 400.8
Description: Mouse polyclonal to Ribonuclease Inhibitor

anti-Ribonuclease Inhibitor

YF-PA14406 50 ug
EUR 435.6
Description: Mouse polyclonal to Ribonuclease Inhibitor

anti-Ribonuclease Inhibitor

YF-PA14407 100 ul
EUR 483.6
Description: Rabbit polyclonal to Ribonuclease Inhibitor

anti-Ribonuclease Inhibitor

YF-PA14408 100 ug
EUR 483.6
Description: Rabbit polyclonal to Ribonuclease Inhibitor

Anti-Ribonuclease Inhibitor/RNH1 Antibody

PB9885 100ug/vial
EUR 400.8

Anti-Ribonuclease Inhibitor (3F5)

YF-MA15221 100 ug
EUR 435.6
Description: Mouse monoclonal to Ribonuclease Inhibitor

Ribonuclease inhibitor Antibody

20-abx137320
  • EUR 844.80
  • EUR 393.60
  • EUR 276.00
  • 100 ug
  • 20 ug
  • 5 ug

Ribonuclease inhibitor

RB0478 5KU
EUR 185.28

Ribonuclease inhibitor Antibody / RNH1

R31956 100 ug
EUR 419

Ribonuclease Inhibitor Antibody / RNH1

RQ5935 100 ug
EUR 419

RNaseOFF ribonuclease Inhibitor

M1238-4000
EUR 307.2

Placenta Ribonuclease Inhibitor

Z5040001 5000 units
EUR 379.2
Description: Working with the fragile RNA molecules requires a great deal of caution, especially when it comes to protecting them from all the RNases that are virtually everywhere. Ensure a successful reverse transcription PCR by protecting you RNAs with our RNase inhibitor.

Rabbit Polyclonal antibody Anti-CRBN

Anti-CRBN 50 µg
EUR 418.8

Anti-CRF-RI antibody

STJ96855 200 µl
EUR 236.4
Description: Rabbit polyclonal to CRF-RI.

Anti-CRF-RI antibody

STJ92473 200 µl
EUR 236.4
Description: Rabbit polyclonal to CRF-RI.

Anti-mouse TNF-RI antibody

STJ16100930 1 mL
EUR 541.2

Anti-TG beta RI antibody

STJ95992 200 µl
EUR 236.4
Description: Rabbit polyclonal to TGFbeta RI.

Ribonuclease/Angiogenin Inhibitor 1 (RNH1) Antibody

20-abx115215
  • EUR 878.40
  • EUR 477.60
  • 150 ul
  • 50 ul

Ribonuclease/angiogenin Inhibitor 1 (RNH1) Antibody

20-abx003000
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Ribonuclease/angiogenin Inhibitor 1 (RNH1) Antibody

abx026812-400ul 400 ul
EUR 627.6

Ribonuclease/angiogenin Inhibitor 1 (RNH1) Antibody

abx026812-80l 80 µl
EUR 343.2

Ribonuclease/angiogenin Inhibitor 1 (RNH1) Antibody

20-abx211145
  • EUR 493.20
  • EUR 360.00
  • 100 ul
  • 50 ul

Ribonuclease/angiogenin Inhibitor 1 (RNH1) Antibody

20-abx211146
  • EUR 493.20
  • EUR 360.00
  • 100 ul
  • 50 ul

Ribonuclease/angiogenin Inhibitor 1 (RNH1) Antibody

abx237365-100ug 100 ug
EUR 610.8

Ribonuclease/angiogenin Inhibitor 1 (RNH1) Antibody

abx237366-100ug 100 ug
EUR 661.2

anti-Fc epsilon RI

YF-PA11731 100 ug
EUR 483.6
Description: Rabbit polyclonal to Fc epsilon RI

anti-Fc epsilon RI

YF-PA23697 50 ul
EUR 400.8
Description: Mouse polyclonal to Fc epsilon RI

Human Ribonuclease Inhibitor ELISA kit

E01R0052-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Human Ribonuclease Inhibitor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Ribonuclease Inhibitor ELISA kit

E01R0052-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Human Ribonuclease Inhibitor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Ribonuclease Inhibitor ELISA kit

E01R0052-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Human Ribonuclease Inhibitor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Ribonuclease Inhibitor ELISA kit

E04R0052-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Rabbit Ribonuclease Inhibitor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Ribonuclease Inhibitor ELISA kit

E04R0052-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Rabbit Ribonuclease Inhibitor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Ribonuclease Inhibitor ELISA kit

E04R0052-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Rabbit Ribonuclease Inhibitor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Ribonuclease Inhibitor ELISA kit

E06R0052-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Goat Ribonuclease Inhibitor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Ribonuclease Inhibitor ELISA kit

E06R0052-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Goat Ribonuclease Inhibitor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Ribonuclease Inhibitor ELISA kit

E06R0052-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Goat Ribonuclease Inhibitor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Ribonuclease Inhibitor ELISA kit

E08R0052-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Canine Ribonuclease Inhibitor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Ribonuclease Inhibitor ELISA kit

E08R0052-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Canine Ribonuclease Inhibitor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Ribonuclease Inhibitor ELISA kit

E08R0052-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Canine Ribonuclease Inhibitor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Ribonuclease Inhibitor ELISA kit

E07R0052-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Porcine Ribonuclease Inhibitor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Ribonuclease Inhibitor ELISA kit

E07R0052-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Porcine Ribonuclease Inhibitor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Ribonuclease Inhibitor ELISA kit

E07R0052-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Porcine Ribonuclease Inhibitor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Ribonuclease Inhibitor ELISA kit

E03R0052-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Mouse Ribonuclease Inhibitor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Ribonuclease Inhibitor ELISA kit

E03R0052-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Mouse Ribonuclease Inhibitor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Ribonuclease Inhibitor ELISA kit

E03R0052-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Mouse Ribonuclease Inhibitor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Ribonuclease Inhibitor ELISA kit

E02R0052-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Rat Ribonuclease Inhibitor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Ribonuclease Inhibitor ELISA kit

E02R0052-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Rat Ribonuclease Inhibitor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Ribonuclease Inhibitor ELISA kit

E02R0052-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Rat Ribonuclease Inhibitor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Ribonuclease Inhibitor ELISA kit

E09R0052-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Monkey Ribonuclease Inhibitor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Ribonuclease Inhibitor ELISA kit

E09R0052-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Monkey Ribonuclease Inhibitor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Ribonuclease Inhibitor ELISA kit

E09R0052-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Monkey Ribonuclease Inhibitor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Anti-Ribonuclease 7 Antibody

STJ60034 100 µg
EUR 508.8

Anti-Ribonuclease 7 Antibody

STJ60035 100 µg
EUR 508.8

Anti-Ribonuclease 7 Antibody

STJ60036 100 µg
EUR 508.8

Anti-ribonuclease 8 Antibody

STJ60037 100 µg
EUR 508.8

anti- Fc epsilon RI alpha antibody

FNab03058 100µg
EUR 702
Description: Antibody raised against Fc epsilon RI alpha

Anti-Fc epsilon RI alpha antibody

PAab03058 100 ug
EUR 494.4

Guinea pig Ribonuclease Inhibitor ELISA kit

E05R0052-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Guinea pig Ribonuclease Inhibitor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig Ribonuclease Inhibitor ELISA kit

E05R0052-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Guinea pig Ribonuclease Inhibitor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig Ribonuclease Inhibitor ELISA kit

E05R0052-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Guinea pig Ribonuclease Inhibitor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Rnh1/ Ribonuclease inhibitor ELISA Kit

E1275Mo 1 Kit
EUR 685.2

ELISA kit for Human Ribonuclease inhibitor

EK3409 96 tests
EUR 663.6
Description: Enzyme-linked immunosorbent assay kit for quantification of Human Ribonuclease inhibitor in samples from serum, plasma, tissue homogenates and other biological fluids.

Chicken Ribonuclease Inhibitor (RNH1) ELISA Kit

abx356259-96tests 96 tests
EUR 990

Rabbit Ribonuclease Inhibitor (RNH1) ELISA Kit

abx363762-96tests 96 tests
EUR 990

Monkey Ribonuclease Inhibitor (RNH1) ELISA Kit

abx359624-96tests 96 tests
EUR 990

Pig Ribonuclease Inhibitor (RNH1) ELISA Kit

abx361392-96tests 96 tests
EUR 990

Mouse Ribonuclease inhibitor (RNH1) ELISA Kit

abx516953-96tests 96 tests
EUR 801.6

Pig Ribonuclease Inhibitor (RNH1) ELISA Kit

abx516954-96tests 96 tests
EUR 990

Rat Ribonuclease inhibitor (RNH1) ELISA Kit

abx516955-96tests 96 tests
EUR 801.6

Human Ribonuclease inhibitor (RNH1) ELISA Kit

abx250903-96tests 96 tests
EUR 848.4

Human Ribonuclease inhibitor (RNH1) ELISA Kit

abx253105-96tests 96 tests
EUR 848.4

Human RNH1(Ribonuclease inhibitor) ELISA Kit

EH1611 96T
EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.938 ng/ml

Human RNH1/ Ribonuclease inhibitor ELISA Kit

E2837Hu 1 Kit
EUR 685.2

Human Ribonuclease inhibitor, RNH1 ELISA KIT

ELI-04719h 96 Tests
EUR 988.8

Mouse Ribonuclease inhibitor, Rnh1 ELISA KIT

ELI-04721m 96 Tests
EUR 1038

Porcine Ribonuclease inhibitor, RNH1 ELISA KIT

ELI-04722p 96 Tests
EUR 1113.6

anti-Ribonuclease T2

YF-PA15757 50 ug
EUR 435.6
Description: Mouse polyclonal to Ribonuclease T2

Anti-Phospho-TG beta RI (S165) antibody

STJ91351 200 µl
EUR 236.4
Description: TGFbeta RI is a protein encoded by the TGFBR1 gene which is approximately 55,9 kDa. TGFbeta RI is localised to the cell membrane. It is involved in apoptotic pathways and the PAK pathway. It is a heteromeric complex that transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation, differentiation and extracellular matrix production. TGFbeta RI is expressed in all human tissues and is most abundant in the placenta. Mutations in the TGFBR1 gene may result in Loeys-Dietz syndrome. STJ91351 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This primary antibody specifically binds to endogenous TGFbeta R protein which only binds about S165 when S165 is phosphorylated.

RI-1

A3764-10 10 mg
EUR 240
Description: RI-1 Description:IC50: 5~30 ?M [1]RAD51 is a eukaryote gene, encoding RAD51 protein that participates in DNA damage induction and complex signal pathway of cell cycle checkpoint of homologous recombination in cells.

RI-1

A3764-5 5 mg
EUR 164.4
Description: RI-1 Description:IC50: 5~30 ?M [1]RAD51 is a eukaryote gene, encoding RAD51 protein that participates in DNA damage induction and complex signal pathway of cell cycle checkpoint of homologous recombination in cells.

RI-1

A3764-5.1 10 mM (in 1mL DMSO)
EUR 174
Description: RI-1 Description:IC50: 5~30 ?M [1]RAD51 is a eukaryote gene, encoding RAD51 protein that participates in DNA damage induction and complex signal pathway of cell cycle checkpoint of homologous recombination in cells.

RI-1

A3764-50 50 mg
EUR 756
Description: RI-1 Description:IC50: 5~30 ?M [1]RAD51 is a eukaryote gene, encoding RAD51 protein that participates in DNA damage induction and complex signal pathway of cell cycle checkpoint of homologous recombination in cells.

RI-2

B5881-10 10 mg
EUR 616.8
Description: Description:IC50: 44.17 ?MHomologous recombination (HR) is an essential process in cells that provides repair of DNA double-strand breaks and lesions that block DNA replication. RAD51 is an evolutionarily conserved protein that is central to HR.

RI-2

B5881-5.1 10 mM (in 1mL DMSO)
EUR 448.8
Description: Description:IC50: 44.17 ?MHomologous recombination (HR) is an essential process in cells that provides repair of DNA double-strand breaks and lesions that block DNA replication. RAD51 is an evolutionarily conserved protein that is central to HR.

RI-2

B5881-50 50 mg
EUR 1730.4
Description: Description:IC50: 44.17 ?MHomologous recombination (HR) is an essential process in cells that provides repair of DNA double-strand breaks and lesions that block DNA replication. RAD51 is an evolutionarily conserved protein that is central to HR.

RI-1

B1823-25
EUR 652.8

RI-1

B1823-5
EUR 210

RI-1

HY-15317 5mg
EUR 183.6

RI-2

HY-16904 100mg
EUR 3531.6

Suavissimoside RI

TBW01280 10mg Ask for price

Anti-Ribonuclease 3/RNASE3 Antibody

A03115-1 100ug/vial
EUR 400.8

Anti-Ribonuclease A/RNASE1 Antibody

PA1507 100ug/vial
EUR 352.8

CRF-RI Polyclonal Antibody

ABP51051-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of CRF-RI from Human, Mouse, Rat. This CRF-RI antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human CRF-RI at AA range: 50-130

CRF-RI Polyclonal Antibody

ABP51051-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of CRF-RI from Human, Mouse, Rat. This CRF-RI antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human CRF-RI at AA range: 50-130

CRF-RI Polyclonal Antibody

ABP51051-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of CRF-RI from Human, Mouse, Rat. This CRF-RI antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human CRF-RI at AA range: 50-130

TGFBeta RI Polyclonal Antibody

ABP52595-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of TGFBeta RI from Human, Mouse, Rat. This TGFBeta RI antibody is for WB, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human TGF? RI around the non-phosphorylation site of S165

TGFBeta RI Polyclonal Antibody

ABP52595-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of TGFBeta RI from Human, Mouse, Rat. This TGFBeta RI antibody is for WB, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human TGF? RI around the non-phosphorylation site of S165
Useful Magnetic Resonance Imaging (fMRI) information have been collected whereas contributors accomplished selective consideration and response inhibition duties designed and balanced for inside or cross-task comparisons. Earlier analysis using this dataset has but to discover associations between mind perform and cognitive evaluation scores or variations in neural processes throughout stimuli options making this dataset helpful for its future contributions to the sector in addition to replication of prior findings.

Leave a Reply

Your email address will not be published.